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Depression Treatment
That Goes Beyond Medication.

When antidepressants haven’t worked — or stopped working — TMS Therapy offers a non-drug path forward that’s FDA-approved, covered by most insurance, and proven to produce lasting results.

✓  Medication-Free
✓  Non-Invasive
✓  Covered by Most Insurance
✓  FDA-Approved

How TMS Treats Depression

Depression is rooted in the brain — specifically in the dysregulation of the dorsolateral prefrontal cortex (DLPFC) and the circuits that control mood, motivation, and emotional response. TMS Therapy targets these circuits directly, delivering gentle magnetic pulses that stimulate neurochemical production, restore healthy brain activity, and rebalance the systems that depression disrupts. For many patients, this is the first treatment that has addressed the actual source of their depression rather than masking symptoms.

Depression treatment with TMS therapy at NeuroStim TMS: patient receiving non-invasive, medication-free treatment for Major Depressive Disorder

Unlike antidepressants, which circulate throughout the entire body and can cause weight gain, fatigue, sexual dysfunction, and emotional blunting, TMS is non-systemic. It works precisely at the brain circuit level — where depression actually lives — without affecting the rest of the body. This is why TMS produces results for many patients who have not responded to medication, and why the side effect profile is dramatically better than most pharmacological options.

There’s no sedation, no hospitalization, and no downtime. Patients sit comfortably in a chair during each 15-to-30-minute session, remain fully awake, and drive themselves home afterward. Most return to work and daily activities the same day they receive treatment.

Industry Leading TMS Doctors & Staff

71.5%
Significant Improvement
46.4%
Full Remission
300+
Patients Treated Daily
98%
Patient Satisfaction Rate

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What Is Treatment-Resistant Depression?

Treatment-resistant depression (TRD) is defined as depression that has not responded adequately to two or more antidepressant medications at appropriate doses and durations. It affects a significant portion of people with Major Depressive Disorder (MDD) — and it is one of the most common reasons patients come to NeuroStim TMS. If antidepressants haven’t worked for you, you are not alone, and you are not out of options.

TRD does not mean your depression is untreatable — it means the treatments you’ve tried haven’t worked yet. TMS Therapy was specifically developed and FDA-approved as a next-step treatment for exactly this population. At NeuroStim TMS, 71.5% of our patients experience significant improvement and 46.4% achieve full remission — many of them after years of trying medications that didn’t provide adequate relief.

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Frequently Asked Questions

How Effective Is TMS for Depression?+

At NeuroStim TMS, 71.5% of patients experience significant improvement in their depression symptoms and 46.4% achieve full remission. These figures reflect our real-world patient population — including many with treatment-resistant depression who had not responded to prior medication trials.

Even patients who don’t reach full remission typically report meaningful life improvements — better sleep, improved concentration, renewed motivation, and the ability to reconnect with people and activities that depression had taken from them.

What Is Treatment-Resistant Depression?+

Treatment-resistant depression (TRD) is defined as depression that has not improved adequately after trying at least two different antidepressant medications at appropriate doses. This is more common than most people realize — a significant portion of people diagnosed with Major Depressive Disorder (MDD) do not achieve remission with medication alone.

TMS was FDA-approved specifically for this population and has strong evidence for patients who have been through multiple antidepressant trials without sufficient relief. A free consultation with our clinical team can help determine whether TMS is the right next step for you.

How Is TMS Different From Antidepressants?+

Antidepressants work systemically — they travel through the bloodstream and affect receptors throughout the entire body, which is why they cause side effects like weight gain, sexual dysfunction, fatigue, nausea, and emotional blunting. They also take weeks to determine if they’re working, and many patients cycle through multiple medications before finding one with acceptable results.

TMS is non-systemic — it uses magnetic pulses to target only the specific brain circuits involved in depression. Because it doesn’t enter the bloodstream, TMS doesn’t cause the systemic side effects of medication. And because it works at the source of depression rather than masking symptoms, many patients find the relief is more complete and more durable.

Does Insurance Cover Depression Treatment With TMS?+

Yes. TMS is covered by most major insurance plans for patients with Major Depressive Disorder who have not had adequate response to at least one antidepressant. NeuroStim TMS is in-network with Premera Blue Cross, BCBS of Arizona, Regence, United Healthcare, Aetna, TriCare, VA/TriWest, and Kaiser.

Our insurance team handles all benefits verification and prior authorization before your first appointment. You’ll know exactly what’s covered before treatment begins.

How Long Does Depression Treatment With TMS Take?+

A standard TMS course for depression is 30 to 36 sessions over six to seven weeks, with one 15-to-30-minute session per day on weekdays. There is no sedation and no recovery time — patients continue working and daily activities throughout the entire treatment period.

Some patients begin noticing improvement within the first one to two weeks. For others, the shift comes later in the course. NeuroStim also offers Accelerated TMS and our proprietary One-Day TMS™ protocol for eligible patients who need a compressed timeline.

Can TMS Help If My Antidepressants Stopped Working?+

Yes — this is one of the most common situations we see. Antidepressants can lose effectiveness over time, a phenomenon sometimes called antidepressant tachyphylaxis. When this happens, patients are often left cycling through new medications in search of something that works again. TMS works through a completely different mechanism, so prior medication response — or lack of it — does not predict how you’ll respond to TMS.

Many of our patients come to us after years on antidepressants that worked initially and then stopped. TMS offers a path to relief that doesn’t depend on the same receptor systems those medications target.

Covered by Most Major Insurance Plans

Premera Blue Cross
BCBS of Arizona
Regence
United Healthcare
Aetna
TriCare
VA / TriWest
Kaiser

If antidepressants haven’t given you the relief you need, there’s another path.

Ready to Find a New Path Forward?

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